By Annie Reuter

U2 guitarist The Edge has become the first rock artist ever to play the historic Sistine Chapel in Italy.

Related: The Edge Compares New U2 Album to ‘Zooropa’

On Saturday (April 30), The Edge performed an unplugged set backed by Irish teenagers. The concert included U2’s “Yahweh,” “Ordinary World,” and “Walk On,” as well as a cover of Leonard Cohen’s “If it Be Your Will.”

“When I was asked to perform in the Sistine Chapel I didn’t know what to say, because usually there’s ‘this other guy’ who sings,” he told the audience. “So it took me at least, well, 30 seconds to agree to it.”

The Edge was invited to play the chapel as a benefit for participants of a conference on regenerative medicine. It’s a cause he could relate to since his daughter was diagnosed with leukemia in 2006. In 2007, The Edge joined the board of the Angiogenesis Foundation.

“I can tell this is a really cool audience, because normally when I mention angiogenesis people’s eyes glaze over,” he said during the show. “But you all understand what I am talking about.”

In an interview earlier this year, the Edge compared U2’s forthcoming album to 1993’s Zooropa. He said producer Brian Eno “would love to see us making albums a bit more like that. Where we go, ‘You know what? We’re not going to second-guess any of this. Let’s just go for it.’ I think there’s a quality you get when there’s a certain momentum to the process.”


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